When I used to use synths live, I always went DI->PA. Sometimes this was good, but often the broad frequency range of a wide-open synth either stepped all over the rest of the band, or was masked by them.
In DAW recording, I've been messing around with adding saturation, distortion, and speaker resonance to synths using a VST, and I like all the coloration it provides. Depending on the patch, it can really help the synth pop out of the mix.
So I wanted to ask about your thoughts and experiences with (non-PA-type) amplification with your synths. What kind of tomfoolery are you up to?